Dr. Chandan Mitra, Professor & Head
cm.phyl@presidencycollegekolkata.ac.in,
chandan_mitrapresi@yahoo.com
Area of Specialisation: Endocrinology & Reproductive Physiology

Dr. Chandan Mitra is the Professor and Head of the Department of Physiology, Presidency College, Kolkata. He received Master Degree in Physiology from Calcutta University in 1970. In 1971, joined as a CSIR Junior Research Fellow at the Indian Institute of Experimental Medicine (IIEM), currently known as IICB, Jadavpur in their Pharmacology & Experimental Therapeutics Division. In 1973 joined the Research & Development Division of Dey’s Medical Manufacturing Ltd., Kolkata, as a Research Pharmacologist. He received his PhD in Physiology from the University of Calcutta, in 1976. He started his teaching career in 1975 at Hooghly Mohsin College, Hooghly, West Bengal. He began his faculty career in the Department of Physiology at Presidency College in 1984 and was promoted to Professor in 1988. He is the senior most Professor of Physiology in the entire educational service of West Bengal, which includes all Universities, Government, Private and Trustee Colleges, since last 12 years.

Areas of Interest
Drug Screening and Drug Research
Toxicological Research
Endocrinology and Reproductive Physiology
Environmental Studies
Demographic Studies
Work Physiology & Ergonomics

Recent Publications
Role of peritoneal macrophages and lymphocytes in the development of hypogonadal osteoporosis in an ovariectomized rat model: possible phytoestrogenic efficacy of oil extract of garlic to preserve skeletal health
Phytotherapy Research, 21(11): 1045-54, 2007

Role of oil extract of garlic (Allium sativum linn.) on intestinal transference of calcium and its possible correlation with preservation of skeletal health in an ovariectomized rat model of osteoporosis.
Phytotherapy Research 20(5); 408-415, 2006.

Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison to the effects of lovastatin and 17b estradiol.
Phytotherapy Research 20(1); 21-27, 2006.

Working postures of tea pluckers and its interrelationship with their plucking efficiency.
Occupational Ergonomics 6: 143-157, 2006.

Synergistic effect of folic acid and Vitamin B12 in ameliorating arsenic-induced oxidative damage in pancreatic tissue of rat.
Journal of Nutritional Biochemistry 17 (5); 319-327, 2006.

Aqueous extract of black tea (Camellia sinensis) prevents ethanol+cholecystokinin- induced pancreatitis in a rat model.
Life Science 78(19): 2194-2203, 2006.

Area of Research
Management of Osteoporosis : Role of Black Tea
Management of Osteoporosis : Role of Garlic
Heat stress Tolerance in Man : Role of Indian Herbs
Nutritional Management of Arsenic Toxicity
Posture, Comfort and Productivity Linked studies in Tea Pluckers of Eastern India : An Ergonomical Study
Work Environment and Health Aspects of Workers of Different Tea Processing Units of Eastern India
Management of obesity-induced liver and bone pathophysiologic changes

Ongoing Research Projects
A cohort study on urban based menopausal women to examine the role of garlic cloves (Allium sativum Linn.) as a possible anti-osteoporotic natural therapeutic agent.
University Grants Commission (UGC), Govt. of India

A study to evaluate the possible ameliorating effects of Black Tea Extract (BTE) on obesity-induced liver and bone pathophysiologic changes.
National Tea Research Foundation (NTRF), Govt. of India

A simple but cost effective dietary management strategy against Arsenic-induced toxicity
Department of Science & Technology (DST), Govt. of West Bengal

A productivity improvement-linked study on women tea pluckers of Eastern India with special considerations to their working comfort, welfare and health status
National Tea Research Foundation (NTRF), Govt. of India

Role of Indian Ayurvedic Herbs on Heat Stress Tolerance in Man
Defence Research & Development Organisation (DRDO), Ministry of Defence, Govt. of India, New Delhi

Research Group
Present Members
Mr. Asankur Sekhar Das (Doctoral)
Mr. Subhra Chattopadhyay (Doctoral)
Ms. Anasuya Maiti (Doctoral)
Ms. Sangita Majumdar (Doctoral)
Ms. Subhra Karmakar (Doctoral)
Ms. Pritikana Saha (Doctoral)
Dr. Dolan Das (Post-Doctoral)
Dr. Maitrayee Mukherjee (Post-Doctoral)

Former Members
Dr. Purosuttom Pramanik
Dr. Srabani Chanda
Dr. Nazrul Islam
Dr. Indrajit Chatterjee
Dr. Sandip Mukherjee
Dr. Dolan Das (Currently Post-Doctoral)
Dr. Maitrayee Mukherjee (Currently Post-Doctoral)
Mr. Soumendra Darbar
Sm Piyal Mukherjee

Teaching Course Taught
Nerve Muscle Physiology
Special Sense
Nervous System
Endocrinology
Population Biology
Sports & Ergonomics

List of Publication
Role of peritoneal macrophage and lymphocytes in the development of hypogonadal osteoporosis in an ovariectomized rat model: possible chemopreventive efficacy of oil extract of garlic to preserve skeletal health.
Phytotherapy Research 21(11): 1045-54, 2007

Role of oil extract of garlic (Allium sativum Linn.) on intestinal transference of calcium and its possible correlation with preservation of skeletal health in an oophorectomized rat model of osteoporosis.
Phytotherapy Research, 20 (5): 408-415, 2006.

Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: Comparison to the effects of lovastatin and 17ß estradiol.
Phytotherapy Research, 20 (1): 21-27, 2006.

Working postures of tea pluckers and its interrelationship with their plucking efficiency.
Occupational Ergonomics, 6: 143-157, 2006.

Synergistic effect of folic acid and vitamin B12 in ameliorating arsenic-induced oxidative damage in pancreatic tissue of rat.
Journal of Nutritional Biochemistry, 17 (5) :319-327,2006.

Aqueous extract of black tea (Camellia sinensis) prevents ethanol + cholecystokinin – induced pancreatitis in a rat model.
Life Science, 78(19):2194-2203,2006

Phytoestrogenic effects of black tea extract (Camellia sinensis) in an oophorectomized rat (Rattus norvegicus) model of osteoporosis.
Life Sciences, 77: 3049-3057, 2005.

Aqueous extract of black tea (Camellia sinensis) prevents chronic ethanol toxicity.
Current Science, 88(6) :952-961,2005

Arsenic – generates oxidative stress and islet cell toxicity in rabbit.
Current Science, 86(6): 854-857, 2004

Evidence for a prospective anti-osteoporosis effect of aqueous black tea (Camellia sinensis) extract in a bilaterally ovariectomized rat model.
Asia Pacific Journal of Clinical Nutrition, 13 (2) : 210 – 216, 2004.

Prevention of bone loss by oil extract of garlic (Allium sativum Linn.) in an ovariectomized rat model of osteoporosis.
Phytotherapy Research, 18 : 389-394,2004.

Dietary intervention affects arsenic-generated nitric oxide and reactive oxygen intermediate toxicity in islet cells of rats
Current Science, .85 (6): 786-793, 2003

Effects of different intensities of cold stress on certain physiological phenomena related to skeletal health in a hypogonadal rat model.
J. Physiol. Pharmacol., 51 (4):857-870. 2000.

Effects of a high intake of unsaturated and saturated oils on intestinal transference of calcium and calcium mobilization from bone in an ovariectomized rat model of osteoporosis.
Asia Pacific J Clin Nutr., 8(2) : 115-120, 1999.

Cold stress facilitates calcium mobilization from bone in an ovariectomized rat model of osteoporosis. Jap. J. Physiol., 48: 49 – 55, 1998.

High-Lipid diet intake is a possible predisposing factor in the development of hypogonadal osteoporosis.
Jap. J. Physiol., 46: 383 - 388, 1996.

Mechanism of Chloramphenicol-induced modulation of mouse ileal motility.
Jap. J. Med. Sci. & Biol., .48, 1995

Mechanism of inhibition of smooth muscle of guineapig taenia coli by Chloramphenicol.
J. Physiol. Pharmacol.(Pol. Acad. Sci.)., 45(1): 132, 1994

The effect of Chloramphenicol on mucosal transference of glucose in mice : the role of intestinal alkaline phosphatase in this process.
J. Physiol. Pharmacol.(Pol. Acad. Sci.)., 44(4): 351, 1993

Vasomotor actions and smooth muscle relaxant properties of some intermediates of Chloramphenicol.
Current Science ., 50: 14, 1981

Inhibition of rat liver mitochondrial monoamine oxidase by Chloramphenicol and 2-Amino-1-p-nitrophenylpropane-1, 3-diol.
J. Pharm. Sci (USA)., 67: 480,1978

Smooth muscle relaxant properties and vasomotor actions of 2-Amino-1-p-nitrophenylpropane 1, 3-diol.
J. Pharm. Sci. (USA)., 66 : 1239, 1977

Muscle relaxant properties of Chloramphenicol
J. Pharm. Sci. (USA).,65: 704, 1976

Antihistaminic effect of a new Piperazine derivative,1-Phenoxy-2-(N-methyl-piperazino)-3-ephedrinopropane monohydrochloride.
Ind. J. Exp. Biol., 12: 138,1974

Book Chapter
Osteoporosis-an overview : Its possible therapeutic management by phyto-oestrogens : In “Medicinal Properties of Tea” published by Oxford & IBM Publishing Co. Pvt. Ltd, USA and New Delhi (2005).